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KMID : 0363320130340040478
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Journal of Korean Oriental Internal Medicine
2013 Volume.34 No. 4 p.478 ~ p.483
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Pancytopenia Improves with Compromised Liver Function in A Hepatocellular Carcinoma Patient Treated by Modified Sipjeondaebo-tang
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Kim Jong-Min
Jun Hyung-Joon
Cho Chong-Kwan
Lee Yeon-Weol
Yoo Hwa-Seung
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Abstract
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Objectives : To observe the therapeutic effects of an oriental herbal prescription in a hepatocellular carcinoma patient with splenomegaly and pancytopenia.
Methods : Modified Sipjeondaebo-tang was prescribed three times a day to a hepatocellular carcinoma patient with splenomegaly and pancytopenia. Laboratory tests were carried out regularly to observe the therapeutic effects of the oriental herbal prescription for pancytopenia.
Results : When treated with modified Sipjeondaebo-tang including Cinnamomi Cortex, the levels of white blood cells, red blood cells, hemoglobin, and hematocrit increased. However, aspartate transaminase, alanine transaminase, alkaline phosphatase, gamma-glutamic transpeptidase, total bilirubin, direct bilirubin levels also increased.
Conclusions : Administering modified Sipjeondaebo-tang with Cinnamomi Cortex showed effect in improving pancytopenia but an increase in liver enzyme levels was also observed.
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KEYWORD
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hepatocellular carcinoma, splenomegaly, pancytopenia, Sipjeondaebo-tang (shiquandafu-tang), Cinnamomi Cortex
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